There are some medications that can affect the continued functioning of HRT combination tablets and capsules, as they can sometimes cause irregular bleeding. Hormonal hormone therapy can also affect how some medications work by making them less effective. For example, some hormone replacement therapies may cause epilepsy to not be as well controlled. The two different phases of liver detoxification of sex hormones depend on good levels of all B vitamins. Vitamin C is important for the immune system, for the formation of collagen, it is a powerful antioxidant, and it also helps the body to use iron.
A total of 27,347 women were randomly assigned to hormone therapy (0.625 mg of conjugated estrogen alone or 0.625 mg of conjugated equine estrogen plus 2.5 mg of medroxyprogesterone acetate per day), and 36,282 women were randomly assigned to 1000 mg of elemental calcium (carbonate) plus 400 IU of vitamin D3 per day, each compared to the placebo. The conversion and production of hormones in the adrenal glands is highly dependent on B vitamins, especially B5 (pantothenic acid).
